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Use of GLP-1 drugs and reduction of the need for knee replacement. This would be expected from the impact of weight loss effect, but another study in osteoarthritis found benefit independent of
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retatrutide is a novel triple agonist peptide at the glucagon receptor, GIP receptor, and GLP-1 receptor. 22-24% weight loss at 48 weeks with a similar tolerability profile to #tirzepatide. @LillyPad #medtwitter #endotwitter
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Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide
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