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Mechanisms and implications of the gut microbial modulation of intestinal metabolic processes npj Metabolic Health and Disease Before you grab the tums, here's a few things that can help with GI distress (including reflux and heart burn) from GLP 1 medicines: 1. Eat smaller meals and lower fat intake. You Is Ozempic the Same as Insulin? Dr. Shima Hadidchi MD IBS is not just a sensitivity issueit's an inflammatory condition. For many patients, GLP 1 medications do more than support weight loss. They address one of the root drivers of IBS: inflammation in Let's clear the air about GLP 1 meds and constipation. If you're on Ozempic, Wegovy, or Mounjaro and feeling bloated, backed up, or just off, you're not alone. These meds slow digestion, which Table 2 from DPP 4 Inhibitors in the Management of Type 2 Diabetes Mellitus Semantic Scholar