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Weight loss itself rather than tissue specific signalling of GLP1 is what carries the risk of advancing sarcopenia in older adults. There is nothing unique to GLP1s that lead to lean mass loss, Beyond glycemic control: Roles for sodium glucose cotransporter 2 inhibitors and glucagon like peptide 1 receptor agonists in diabetic kidney disease GLP 1 and GIP: Magic bullet for musculoskeletal diseases? ScienceDirect Ozempic Lawsuits Facing a $2 Billion Problem and Growing Law Firm of Melinda J. Helbock, A.P.C. San Diego GLP 1 drugs are associated with a 35% higher risk of NAION, an eye condition that can cause sudden vision loss. About 6 to 10 extra cases per 10,000 users over 3 years. Rising GLP 1 drug costs challenge employers' budgets Indianapolis News Indiana Weather Indiana Traffic WISH TV